Have you ever wondered if male sweat could affect women’s emotions? Surprisingly, science says yes! Research shows that a special chemical in male underarm sweat can actually help women improve their mood and even influence their hormone levels. This fascinating discovery reveals how natural body scents play a role in human emotional and physiological connections.
Table of Contents
The Key Chemical: Androstadienone
The chemical responsible for this mood-boosting effect is called androstadienone (often abbreviated as AND). It is a steroid-like molecule found in higher concentrations in male sweat, especially under the arms, as well as in other male bodily secretions like saliva. Androstadienone acts as a kind of human chemosignal, similar to pheromones in animals, which subtly affects behavior and physiology.

Scientific Discovery by UC Berkeley
A landmark study led by Dr. Claire Wyart, a postdoctoral fellow at the University of California, Berkeley, published on February 6, 2007, in The Journal of Neuroscience, demonstrated for the first time how smelling androstadienone can significantly affect women’s hormone levels and mood. Dr. Wyart and her team conducted experiments with 48 female undergraduate volunteers who smelled androstadienone samples or a control substance over a two-hour period.
The study found that simply inhaling androstadienone caused the women’s cortisol levels—a hormone related to stress, arousal, and alertness—to rise within 15 minutes and stay elevated for more than an hour. Along with hormonal changes, the women reported improved mood, increased sexual arousal, and physiological signs of alertness such as elevated blood pressure and heart rate.
Importantly, these effects occurred without the women consciously noticing a strong odor, indicating that androstadienone works on a subconscious physiological level.

Why Cortisol Matters
Though commonly known as the “stress hormone,” cortisol has a broader role in regulating mood, cognition, and emotional balance. The increase in cortisol after smelling male sweat suggests a natural way to enhance alertness and positive feelings. This subtle hormonal effect could play a role in human social interactions, attraction, and even reproductive behaviors.
Implications of the Research
This discovery challenges the long-held belief that human pheromones either do not exist or have minimal impact. It suggests that male underarm sweat contains bioactive compounds that can influence women’s feelings and physiology. Dr. Wyart and colleagues propose that this natural chemical signal might one day be used therapeutically to help people with hormonal imbalances, such as those suffering from disorders like Addison’s disease, as a safer alternative to hormone pills.
Further Studies and Expert Opinions
Other scientists have supported these findings, showing that androstadienone and similar chemicals influence women’s sexual response, mood, and brain activation. For example, a 2012 review by researcher J. Verhaeghe confirmed the beneficial effects of 16-androstene pheromones, including androstadienone, on women’s focus and sexuality.
Despite these advances, researchers emphasize the need for more studies on how these chemosignals affect cognition and which receptors in the brain respond to them.
Conclusion
By all data and the research led by Claire Wyart at UC Berkeley in 2007 provides strong scientific evidence that male underarm sweat contains a natural compound, androstadienone, which can positively influence women’s mood and hormone levels. This chemical acts as a human chemosignal that might deepen our understanding of social and biological human interactions, opening doors for new natural mood-enhancing therapies.
Disclaimer: This article is written and verified by healthcare professionals. This article is for educational purposes only. If you found this article helpful, then don’t forget to share it.
